Per the Consolidated Appropriations Act, 2023, scleroderma research is now listed as a Topic Area in the Peer Reviewed Medical Research Program (PRMRP) and not as a separate research program. As such, funding opportunities for scleroderma research can be found here PRMRP.

Vision – To combat scleroderma through a partnership of scientists, clinicians, and consumers

Scleroderma Program Cover Image
Scleroderma’s Research Program Cover Image
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Scleroderma is a poorly understood heterogeneous disease with poor survival, no validated biomarkers, and no effective disease-modifying treatment. Scleroderma, or systemic sclerosis (SSc), presents as a chronic connective tissue multisystem disorder characterized by vasculopathy, autoimmunity, inflammation, and fibrosis. The prevalence of SSc is about 250 cases per million, and the incidence rate is about 20 per million adults, with approximately 70,000 SSc cases in the United States. SSc has the highest mortality rate of any systemic autoimmune disease, with interstitial lung disease as the leading cause of disease-related mortality. Although it strikes patients of all ages, including children, incidence is most likely between the ages of 40-60. There is a higher prevalence in some Native American populations. The Scleroderma Research Program was funded by Congress in FY20 and FY21 for a total of $10 million, and the SRP has invested in research focusing on the prevention, detection, diagnosis, and treatment of scleroderma for the benefit of Service Members, Veterans, their families, and the American public.

SRP FY20 Stake Holders Meeting Summary

Congressional Appropriations

Congressional Appropriations

  • $10 million

Funding Summary


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To combat scleroderma through a partnership of scientists, clinicians, and consumers


To fund and facilitate the most promising, highest quality research aimed at understanding mechanisms, improving therapies, and ultimately curing scleroderma for Service Members, Veterans, and the American public

Last updated Sunday, December 31, 1600