DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

Synopsis of Open Program Funding Opportunities


FY23 Amyotrophic Lateral Sclerosis Research Program (ALSRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline  
Pilot Clinical Trial Award (PCTA) Program Announcement
Application Instructions
February 8, 2023
  • The maximum allowable funding for the entire period of performance is $2,000,000 for direct costs.
  • Clinical Care Tier: The maximum allowable funding for the entire period of performance is $1,000,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application (Preproposal):
April 13, 2023
5:00 p.m. Eastern Time

Application:
July 13, 2023
11:59 p.m. Eastern Time
Clinical Biomarker Development Award (CBDA) Program Announcement
Application Instructions
February 8, 2023
  • The maximum allowable funding for the entire period of performance is $750,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 2 years.
Pre-Application (Preproposal):
April 13, 2023
5:00 p.m. Eastern Time

Application:
July 13, 2023
11:59 p.m. Eastern Time
Therapeutic Development Award (TDA) Program Announcement
Application Instructions
February 8, 2023
  • The maximum allowable funding for the entire period of performance is $1,500,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application (Preproposal):
April 13, 2023
5:00 p.m. Eastern Time

Application:
July 13, 2023
11:59 p.m. Eastern Time
Therapeutic Idea Award (TIA) Program Announcement
Application Instructions
February 8, 2023
  • The maximum allowable funding for the entire period of performance is $600,000 for direct costs.
  • Biomarker Option: The maximum allowable funding for the entire period of performance is $750,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 2 years.
Pre-Application (Preproposal):
April 13, 2023
5:00 p.m. Eastern Time

Application:
July 13, 2023
11:59 p.m. Eastern Time

FY23 Autism Research Program (ARP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Career Development Award (CDA) Program Announcement
Application Instructions
March 3, 2023
  • The maximum period of performance is 3 years.
  • The maximum allowable funding for the entire period of performance is $550,000 in direct costs (plus indirect costs).
Pre-Application (Preproposal):
April 19, 2023 5:00 p.m. Eastern Time (ET)

Application:
July 20, 2023 11:59 p.m. ET
Clinical Trial Award (CTA) Program Announcement
Application Instructions
March 3, 2023
  • The maximum period of performance is 4 years.

Single PI:

  • The maximum allowable funding for the entire period of performance is $1,900,000 in direct costs (plus indirect costs).

Early-Career Investigator Partnering PI Option:

  • The maximum allowable funding for the entire period of performance is $2,200,000 in direct costs (plus indirect costs).
Pre-Application (Preproposal):
April 19, 2023 5:00 p.m. Eastern Time (ET)

Application:
July 20, 2023 11:59 p.m. ET
Idea Development Award (IDA) Program Announcement
Application Instructions
March 3, 2023
  • The maximum period of performance is 3 years.

Single PI or Partnering PI Option:

  • The maximum allowable funding for the entire period of performance is $550,000 in direct costs (plus indirect costs).
Pre-Application (Preproposal):
April 19, 2023 5:00 p.m. Eastern Time (ET)

Application:
July 20, 2023 11:59 p.m. ET

FY23 Breast Cancer Research Program (BCRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Clinical Research Extension Award (CREA) Program Announcement
Application Instructions
February 28, 2023 Clinical Research Extension Award:
  • The maximum allowable funding for the entire period of performance is $5M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Clinical Research Extension Award with Partnering PI Option:
  • The maximum allowable funding for the entire period of performance is $6M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Letter of Intent):

June 6, 2023
5:00 p.m. Eastern Time

Application:
June 22, 2023
11:59 p.m. Eastern Time
ERP

FY23 Epilepsy Research Program (ERP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Idea Development Award (IDA) Program Announcement
Application Instructions
February 3, 2023 Level I:
  • The maximum allowable funding for the entire period of performance is $450,000 for direct costs.
  • The maximum period of performance is 3 years.
Level II:
  • The maximum allowable funding for the entire period of performance is $650,000 for direct costs.
  • The maximum period of performance is 3 years.
Pre-Application
(Letter of Intent):
May 19, 2023
5:00 p.m. Eastern Time

Application:
June 23, 2023
11:59 p.m. Eastern Time
Research Partnership Award (RPA) Program Announcement
Application Instructions
February 3, 2023
  • The maximum allowable funding for the entire period of performance is $1,200,000 for direct costs.
  • The maximum period of performance is 3 years.
Pre-Application
(Letter of Intent):
May 19, 2023
5:00 p.m. Eastern Time

Application:
June 23, 2023
11:59 p.m. Eastern Time
Virtual Post-Traumatic Epilepsy Research Center Faculty Award
(Virtual-P-TERC-F)
Program Announcement
Application Instructions
February 3, 2023
  • The maximum allowable funding for the entire period of performance is $525,000 for direct costs.
  • The maximum period of performance is 3 years.
Pre-Application
(Letter of Intent):
May 19, 2023
5:00 p.m. Eastern Time

Application:
June 23, 2023
11:59 p.m. Eastern Time
Leveraging Research Award (LRA) Program Announcement
Application Instructions
February 3, 2023
  • The maximum allowable funding for the entire period of performance is $250,000 for direct costs.
  • The maximum period of performance is 3 years.
Pre-Application
(Letter of Intent):
May 19, 2023
5:00 p.m. Eastern Time

Application:
June 23, 2023
11:59 p.m. Eastern Time
LCRP

FY23 Lung Cancer Research Program (LCRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Career Development Award
(CDA)
Program Announcement
Application Instructions
February 16, 2023
  • Maximum funding of $375,000 in direct costs (plus indirect costs).
  • Period of performance not to exceed 3 years.
Pre-Application
(Letter of Intent):

May 2, 2023
5:00 p.m. Eastern time (ET)

Letter of Intent is required.

Application:
May 23, 2023
11:59 p.m. ET
Concept Award
(CA)
Program Announcement
Application Instructions
February 16, 2023
  • Maximum funding of $100,000 in direct costs (plus indirect costs).
  • Period of performance not to exceed 1 year.
Pre-Application
(Letter of Intent):

May 2, 2023
5:00 p.m. ET

Letter of Intent is required.

Application:
May 23, 2023
11:59 p.m. ET
Idea Development Award
(IDA)
Program Announcement
Application Instructions
February 16, 2023
  • Maximum funding of $525,000 in direct costs (plus indirect costs).
  • Period of performance not to exceed 3 years.
Pre-Application
(Preproposal):

May 10, 2023
5:00 p.m. ET

Preproposal is required; application submission is by invitation only.

Application:
August 3, 2023
11:59 p.m. ET
Translational Research Award
(TRA)
Program Announcement
Application Instructions
February 16, 2023 Level 1
  • Maximum funding of $900,000 in direct costs (plus indirect costs).
  • Period of performance not to exceed 3 years.
Level 2 – Clinical Trial Option
  • Maximum funding of $1,200,000 in direct costs (plus indirect costs).
  • Period of performance not to exceed 4 years.
Pre-Application
(Preproposal):

May 10, 2023
5:00 p.m. ET

Preproposal is required; application submission is by invitation only.

Application:
August 3, 2023
11:59 p.m. ET

FY23 Ovarian Cancer Research Program (OCRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Ovarian Cancer – Clinical Trial Academy Leadership Award (OCCTALA) Program Announcement
Application Instructions
March 23, 2023
  • The maximum allowable funding for the entire period of performance is $1,750,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Letter of Intent):

May 26, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time
Clinical Trial Award (CTA) Program Announcement
Application Instructions
March 7, 2023
  • The maximum allowable funding for the entire period of performance is $2,000,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Letter of Intent):

May 26, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time
Clinical Translational Research Award (CTRA) Program Announcement
Application Instructions
March 7, 2023
  • The maximum allowable funding for the entire period of performance is $2,000,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Letter of Intent):

May 26, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time
Investigator-Initiated Research Award (IIRA) Program Announcement
Application Instructions
February 16, 2023
  • The maximum allowable funding for the entire period of performance is:
    • $600,000 for direct costs for a single PI.
    • $800,000 for direct costs for Partnering PIs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Preproposal):

April 17, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time
Ovarian Cancer Academy Award - Early-Career Investigator (OCA) Program Announcement
Application Instructions
February 16, 2023
  • The maximum allowable funding for the entire period of performance is $725,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Preproposal):

April 17, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time
Pilot Award (PA) Program Announcement
Application Instructions
February 16, 2023
  • The maximum allowable funding for the entire period of performance is $300,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 2 years.
Pre-Application
(Preproposal):

April 17, 2023
5:00 p.m. Eastern Time

Application:
July 21, 2023
11:59 p.m. Eastern Time

FY23 Peer Reviewed Alzheimer's Research Program (PRARP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Transforming Care Award (TCA) Program Announcement
Application Instructions
March 27, 2023
  • The maximum allowable funding for the entire period of performance is:
    • $1.0 million (M) in total costs for the base option
    • $1.2M in total costs for the CITPO
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Letter of Intent):
May 31, 2023
5:00 p.m. Eastern Time

Application:
July 10, 2023
11:59 p.m. Eastern Time
Transforming Diagnosis Award (TDA) Program Announcement
Application Instructions
March 27, 2023
  • The maximum allowable funding for the entire period of performance is $2.5M for total costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Letter of Intent):
May 31, 2023
5:00 p.m. Eastern Time

Application:
July 10, 2023
11:59 p.m. Eastern Time
Transforming Research Award (TRA) Program Announcement
Application Instructions
March 27, 2023
  • The maximum allowable funding for the entire period of performance is $1.0M for total costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application
(Letter of Intent):
May 31, 2023
5:00 p.m. Eastern Time

Application:
July 10, 2023
11:59 p.m. Eastern Time

FY23 Peer Reviewed Medical Research Program (PRMRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Clinical Trial Award (CTA) Program Announcement
Application Instructions
February 1, 2023 Clinical Trial Option:
  • A funding limit is not defined; requested funding must be appropriate for the scope of work proposed.
  • The maximum period of performance for the clinical trial is 4 years.

Planning Phase with Clinical Trial Option:
  • The maximum allowable funding for the Planning Phase period of performance is $500,000 for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance for the planning phase is 18 months.
  • The maximum period of performance for the clinical trial is 4 years.
Pre-Application
(Preproposal):

April 12, 2023
5:00 p.m. Eastern Time

Application:
July 19, 2023
11:59 p.m. Eastern Time
Focused Program Award (FPA) Program Announcement
Application Instructions
February 1, 2023
  • The maximum allowable funding for the entire period of performance is $7.2 million for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Preproposal):

April 12, 2023
5:00 p.m. Eastern Time

Application:
July 19, 2023
11:59 p.m. Eastern Time
Investigator-Initiated Research Award (IIRA) Program Announcement
Application Instructions
February 1, 2023
  • The maximum allowable funding for the entire period of performance is $1.6 million for direct costs for single investigators and $2.0 million for partnering investigators.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Letter of Intent):

April 19, 2023
5:00 p.m. Eastern Time

Application:
May 31, 2023
11:59 p.m. Eastern Time
Lifestyle and Behavioral Health Interventions Research Award (LBIRA) Program Announcement
Application Instructions
February 1, 2023
  • The maximum allowable funding for the entire period of performance is $3.0 million for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.

Pre-Application
(Letter of Intent):

April 19, 2023
5:00 p.m. Eastern Time

Application:
May 31, 2023
11:59 p.m. Eastern Time
Technology/Therapeutic Development Award (TTDA) Program Announcement
Application Instructions
February 1, 2023 Funding Level 1:
  • The maximum allowable funding for the entire period of performance is $2.0 million for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance for the clinical trial is 4 years.

Funding Level 2:
  • The maximum allowable funding for the entire period of performance is $4.0 million for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance for the clinical trial is 4 years.

Pre-Application
(Letter of Intent):

April 19, 2023
5:00 p.m. Eastern Time

Application:
May 31, 2023
11:59 p.m. Eastern Time

FY23 Spinal Cord Injury Research Program (SCIRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Clinical Trial Award (CTA) Program Announcement
Application Instructions
March 30, 2023
  • The maximum allowable funding for the entire period of performance is $3.0 million (M) for direct costs.
  • Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $3.1M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 4 years.
Pre-Application
(Preproposal):

May 24, 2023
5:00 p.m. Eastern Time

Application:
September 7, 2023
11:59 p.m. Eastern Time
Clinical Translation Research Award (CTRA) Program Announcement
Application Instructions
March 30, 2023
  • The maximum allowable funding for the entire period of performance is $1.25M for direct costs.
  • Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $1.35M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application
(Preproposal):

May 24, 2023
5:00 p.m. Eastern Time

Application:
September 7, 2023
11:59 p.m. Eastern Time
Translational Research Award (TRA) Program Announcement
Application Instructions
March 30, 2023
  • The maximum allowable funding for the entire period of performance is $1.25M for direct costs.
  • Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $1.35M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application
(Preproposal):

May 24, 2023
5:00 p.m. Eastern Time

Application:
September 7, 2023
11:59 p.m. Eastern Time
Investigator-Initiated Research Award (IIRA) Program Announcement
Application Instructions
March 30, 2023
  • The maximum allowable funding for the entire period of performance is $0.5M for direct costs.
  • Early-Career Partnering PI Option: Maximum allowable funding for the entire period of performance is $0.6M for direct costs.
  • Indirect costs may be proposed in accordance with the institution’s negotiated rate agreement.
  • The maximum period of performance is 3 years.
Pre-Application
(Preproposal):

May 24, 2023
5:00 p.m. Eastern Time

Application:
September 7, 2023
11:59 p.m. Eastern Time

FY23 Tuberous Sclerosis Complex Research Program (TSCRP)

Mechanism Program Announcement/Instructions Release Date Funding Amount Submission Deadline
Exploration – Hypothesis Development Award (EHDA) Program Announcement
Application Instructions
March 15, 2023
  • The maximum period of performance is 2 years.
  • The maximum allowable funding for the entire period of performance is $150,000 in direct costs.
  • Indirect costs may be proposed in accordance With the institution's negotiated rate agreement.
Pre-Application
(Letter of Intent):

June 8, 2023
5:00 p.m. Eastern Time (ET)

Application:
July 7, 2023 11:59 p.m. ET
Idea Development Award (IDA) Program Announcement
Application Instructions
March 15, 2023
  • The maximum period of performance is 3 years.
  • The maximum allowable funding for the entire period of performance is $500,000 in direct costs.
  • Indirect costs may be proposed in accordance with the institution's negotiated rate agreement.
Pre-Application
(Letter of Intent):

June 8, 2023
5:00 p.m. Eastern Time (ET)

Application:
July 7, 2023 11:59 p.m. ET
Clinical Translational Research Award (CTRA) Program Announcement
Application Instructions
March 15, 2023
  • The maximum period of performance is 3 years.
  • The maximum allowable funding for the entire period of performance is $1,000,000 in direct costs.
  • The maximum allowable funding for the entire period of performance is $1,150,000 in direct costs for applications including a Partnering PI Option.
  • Indirect costs may be proposed in accordance with the institution's negotiated rate agreement.
Pre-Application
(Letter of Intent):

June 8, 2023
5:00 p.m. Eastern Time (ET)

Application:
July 7, 2023 11:59 p.m. ET